Why ActivEase® Green Lipped Mussel consistently delivers clinically proven results
Supplements containing Green Lipped Mussel (GLM) are becoming increasingly popular but not all GLM is of the same quality, so paying particular attention to quality is critical. Over a decade of research and £1M R&D investment has gone into the development of ActivEase®, the proprietary Green Lipped Mussel extract used in Lintbells’ products.
DELIVERING CLINICAL PROOF
Over the last 40 years, circa 150 publications have been written on the health benefi ts of GLM. From the wealth of scientifi c literature available, it is easy to pick examples of poor studies, or studies using low doses or poor quality GLM. However, a number of well-designed double blind, placebo-controlled studies have been conducted in dogs and cats (Bierer & Bui, 2002; Bui & Bierer, 2003; Hielm-Bjorkman et al, 2013). For those interested, a broader review of the literature has recently been published (Eason et al, 2018). The scientifi c understanding provided by Bierer & Bui was used in the early development of the composition and processing standards required for ActivEase® GLM. The subsequent double blind, placebo-controlled, crossover study conducted by the Royal Veterinary College (data on fi le) further cemented those standards, ensuring that ActivEase® GLM can consistently deliver.
ENSURING CONSISTENT RAW MATERIAL QUALITY IS FUNDAMENTAL
Lintbells has invested a million pounds over the last ten years to deepen the understanding of the chemical composition and associated health benefits of Green Lipped Mussel, and perfect the sourcing and processing of GLM to produce ActivEase®. As a result of this investment, Lintbells has become a GLM world expert. By thoroughly understanding the chemical composition and processing of GLM extracts, it has enabled us to achieve the outcomes shown in our RVC clinical study. A detailed understanding of GLM is needed to be able to source the best quality raw ingredient. We only source GLM from farms with a consistent quality record and can fully trace all batches back to individual growing locations and harvest dates. The local environment, including details such as tidal nutrient fl ow, geographic location, the genus of spat (juvenile mussel) used and the time of year infl uences the optimal time of harvesting for maximum quality. Understanding these details, and the impact they have on the quality of the fi nal product, results in ActivEase® delivering a consistently high and stable essential fatty acid profile.
MAINTAINING QUALITY STANDARDS ON A DAILY BASIS
The attention to detail, that starts with sourcing, continues with our unique processing method. The raw product is stabilised before undergoing a very rapid vacuum drying process reducing the mussels to powder in less than sixty seconds. Starting with a high-quality ingredient and low temperature, rapid processing results in a product with signifi cantly higher levels of omega 3 fatty acids compared with those found in other GLM powders. We perform full fatty acid profi les, looking at over 40 individual fatty acids, lipid class analysis and oxidative stability on each individual ActivEase® batch produced on a daily basis to ensure that the fatty acid profile is always equal to or above that used in our RVC clinical study.
PUSHING THE BOUNDARIES OF RESEARCH
Lintbells continues to invest signifi cantly in furthering the understanding of Green Lipped Mussel. Through a number of research collaborations, a full suite of bioactivity analyses is enabling a far greater understanding of the mechanisms of action, enabling the introduction of product enhancements and directing future research in the field. Furthermore, additional clinical studies are being conducted with globally
recognised veterinary schools to enable further correlation between Green Lipped Mussel composition and clinically valid outcomes in companion animals. Over a decade of research and £1M R&D investment has gone into the development of ActivEase® Green Lipped Mussel. We perform full fatty acid profi les, looking at over 40 individual fatty acids, lipid class analysis and oxidative stability on each individual ActivEase® batch.
To download the full article, click HERE
Bierer, T.L.; Bui, L.M. J. Nutr. 2002, 132, 16345-16365
Bui, L.M.; Bierer, T.L. Vet.Ther. 2003, 4, 397-407
Eason, C. T., Adams, S. L., Puddick, J., Romanazzi, D., Miller, M. R., King, N., Packer, M. A. Vet.
sciences 2018, 5(2), 36
Hielm-Bjorkman, A.; Roine, J.; Elo, K; Lappalainen, A.; Junnila, J.; Laitinen-Vapaavuori, O. BMC
Vet. Res. 2012, 8, 157 A4